Gretchen Reynolds - Phys Ed columnist for the New York Times - wrote:
New science shows very persuasively that standing up about every 20 minutes, even for only a minute or two, reduces your risks of developing diabetes and heart disease.
By standing up, you cause the big muscles in your legs and back to contract, which leads to an increase in certain enzymes that break up fat in the blood stream. You don't have to jog in place or do jumping jacks. Just stand. A very pleasant additional benefit is that standing up every 20 to 30 minutes also seems to prompt the body to burn calories, so you don't gain as much weight from sitting at the office most of the day.
If you can stand up every 20 minutes — even if you do nothing else — you change how your body responds physiologically.
Risks of Sitting
In recent years major international research has been undertaken providing compelling evidence that sitting for more than 4 hours each day can lead to:
Irrespective of your physical activity levels, the outcome of sitting can lead to increased risks of diabetes, obesity, heart disease, cancer, back ache, stiffness, pain, dementia, depression and muscle degeneration.
Benefits of Standing
By having a sit / stand desk users can easily correct posture alignment whilst promoting the following health and work benefits: